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Nicotine Pouches Studies

Nicotine Pouches studies

On this page, we have compiled all the most notable studies about tobacco-free nicotine pouches and discussed their findings. These studies will help you get a better understanding of the health effects of nicotine pouches so you can make an informed decision.

In March 2021, the German Federal Institute for Risk Assessment (BfR) conducted a preliminary evaluation of health risks related to the use of nicotine pouches. The BfR’s findings were subsequently reviewed by various parties, and experimental studies were conducted on different nicotine pouches, which were included in the assessment.

Researchers enrolled 34 healthy adult smokers to determine the nicotine Cmax and AUC0-T of three 4 mg nicotine products (NP, gum, lozenge) under fasting conditions using a randomised crossover method. Overall, the study suggests that NPs could be a promising alternative to traditional nicotine replacement therapies (NRTs) for smokers looking for a more satisfying nicotine source.

This study compares nicotine pouches (NPs) with Swedish snus and nicotine replacement therapies (NRTs), NPs contained lower levels of metals such as arsenic, cadmium, chromium, nickel, and lead, as well as lower levels of nitrosamines, acetaldehyde, and ochratoxin. Formaldehyde content was similar between NPs and snus, but no measured harmful and potentially harmful constituents (HPHCs) were higher in NPs compared to snus.

Preclinical Assessment of Tobacco-Free Nicotine Pouches Demonstrates Reduced In Vitro Toxicity Compared with Tobacco Snus and Combustible Cigarette Smoke
The New Nicotine Pouch Category: A Tobacco Harm Reduction Tool?
Awareness, susceptibility, and use of oral nicotine pouches and comparative risk perceptions with smokeless tobacco among young adults in the United States

Findings from the current investigation suggest that the evaluated tobacco-free nicotine products (TFNPs) hold considerable potential for tobacco harm reduction (THR), even surpassing the established harm reduction qualities of snus.

The analysis in this text offers a possible framework for an all-encompassing evaluation of the nicotine pouch category. Information gathered from the suggested research domains could enhance the understanding of regulatory policy choices concerning this category.

In this study conducted in 2021, 609 young adults, aged between 18 and 25 years, participated in an online survey. Participants provided information regarding their awareness, susceptibility, and utilization of nicotine pouches (NPs), and their perceptions of NPs in comparison to smokeless tobacco products.

Biomarkers of Exposure and Potential Harm in Exclusive Users of Nicotine Pouches and Current, Former, and Never Smokers: Protocol for a Cross-sectional Clinical Study
Estimating the public health impact had tobacco-free nicotine pouches been introduced into the US in 2000

This study, conducted in Denmark and Sweden aimed to shed light on the toxicant exposure and biomarkers linked to the development of smoking-related diseases among users of nicotine products (NPs) in comparison to traditional smokers. Additionally, the study sought to evaluate the potential role of NPs in tobacco harm reduction (THR). This two-center, cross-sectional confinement investigation focused on determining if there are favorable differences in biomarkers of exposure (BoEs) to tobacco toxicants and biomarkers of potential harm (BoPHs) among exclusive NP users when compared to current smokers.

The health consequences of individuals who smoke that transition to a lower-risk nicotine alternative were analyzed for the time between 2000 and 2050, speculating the potential impact if the nicotine pouch ZYN had been introduced to the United States market in the year 2000. The toxicant composition and use of ZYN resemble those of Swedish snus which has proven to pose considerably lower health risks in comparison to smoking. While acknowledging uncertainties, the study’s findings suggest that the introduction of ZYN could lead to a significant reduction in the number of deaths associated with nicotine product usage.

About Nicotine Pouch Studies

Nicotine pouches have become increasingly popular in recent years as a convenient and discrete way to consume nicotine without the harmful effects of tobacco smoke. However, due to their relative novelty on the market, there are still relatively few studies specifically done on tobacco-free nicotine pouches.

Many studies have been conducted on traditional tobacco products like snus and cigarettes, but the same conclusions may not immediately apply to nicotine pouches since they are a different product. It’s important to note that nicotine pouches are tobacco-free and are made with a mixture of nicotine, plant fibers, and other ingredients.

As nicotine pouches gain popularity, more research is being conducted to better understand their effects on health and overall well-being.

On this page website, we have compiled a list of notable studies done on nicotine pouches, but we acknowledge that this list is not exhaustive and there is still much to be learned about this product. As more research is conducted, we will continue to add to this list to provide our readers with the most up-to-date information available. Each study has a link to it so you can read them in full.